Positive and Negative Syndrome Scale (PANSS): Exam Guide
Introduction
The Positive and Negative Syndrome Scale (PANSS) is one of the most widely used clinical assessment tools in psychiatry to measure the severity of symptoms in schizophrenia and related psychotic disorders. Developed by Kay, Opler, and Fiszbein in 1987, PANSS evaluates both positive symptoms (excesses of normal function) and negative symptoms (losses of normal function), as well as general psychopathology. Its structured format makes it highly valuable for both clinical practice and research.
Theory Behind PANSS
The PANSS is grounded in the conceptual distinction between positive and negative symptoms of schizophrenia:
- Positive symptoms: Delusions, hallucinations, and disorganized thinking, representing an excess or distortion of normal functioning.
- Negative symptoms: Apathy, lack of motivation, social withdrawal, and flat affect, representing a reduction in normal functioning.
In addition, PANSS includes general psychopathology items (e.g., anxiety, depression, poor attention, somatic concerns), acknowledging the wide spectrum of schizophrenia-related symptoms.
Applications
- Clinical psychiatry: Assessing symptom severity in schizophrenia.
- Monitoring treatment progress and symptom changes over time.
- Evaluating the effectiveness of medications and psychosocial therapies.
- Research trials for schizophrenia and related disorders.
- Assisting in differential diagnosis of psychotic disorders.
Procedure
- 30-item clinician-rated scale completed after a semi-structured interview (45–60 minutes).
- Each item rated on a 7-point scale (1 = Absent, 7 = Extreme).
- Divided into three subscales:
- Positive Scale (7 items)
- Negative Scale (7 items)
- General Psychopathology Scale (16 items)
Similar/Alternative Tests
- Brief Psychiatric Rating Scale (BPRS)
- Scale for the Assessment of Positive Symptoms (SAPS)
- Scale for the Assessment of Negative Symptoms (SANS)
Age Criteria
- Typically used for adolescents and adults (≥18 years) with schizophrenia or psychotic disorders.
Scales and Scoring
- Positive symptoms: 7–49
- Negative symptoms: 7–49
- General psychopathology: 16–112
- Total score range: 30–210
- Interpretation: Higher scores indicate more severe psychopathology.
Interpretation
- Provides both total severity score and symptom profile (positive vs. negative dominance).
- Useful in planning treatment approaches.
- Example: A patient with higher negative symptom scores may need psychosocial interventions in addition to medication.
Instructions Before Conducting PANSS
- Conduct the interview in a private, quiet setting.
- Establish rapport to ensure patient comfort and cooperation.
- Use open-ended questions with probing for clarification.
- Ensure the interviewer is properly trained in PANSS scoring.
Drawbacks
- Time-consuming (45–60 minutes).
- Requires specialized training to administer and interpret.
- Inter-rater variability may occur due to subjective judgment.
- Not suitable for severely acute patients unable to participate in interviews.
Precautions
- Should not be used alone—combine with case history and clinical evaluation.
- For consistency, repeated assessments should ideally be done by the same clinician.
- Be mindful of cultural differences in symptom expression.
Possible Questions for Evaluation
- Who developed PANSS and in which year?
- How many items are included in PANSS?
- What are the three main subscales?
- What is the total scoring range of PANSS?
- What is the primary application of PANSS in clinical practice?
Example and Case Study
Case: A 28-year-old male with schizophrenia is admitted with symptoms of relapse including auditory hallucinations and delusions.
- Positive Score = 32 (moderate)
- Negative Score = 20 (mild)
- General Psychopathology = 45 (moderate)
- Total Score = 97
Interpretation: This profile suggests a predominance of positive symptoms. Treatment adjustment is initiated with antipsychotic medication, and PANSS is repeated every two weeks to track improvement.
Conclusion
The Positive and Negative Syndrome Scale (PANSS) remains one of the most reliable and validated tools for assessing schizophrenia. For psychology students, understanding its theory, application, scoring, and limitations is crucial for both exams and clinical practice. With its structured scoring, PANSS helps bridge academic knowledge with real-world psychiatric care.
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